Translational Research in Neurodevelopmental Disorders: Development of Etiology-Based Animal Models

To date, al-though various clinical studies such as molecular geneticstudies and neuroimaging analyses have been reported, theetiology of AD/HD has yet to be revealed. Animal modelscan be useful to facilitate our understanding of this disorderbecause they are helpful in studying the behavioral conse-quences. In this review, we focus on current animal modelsof AD/HD.2. HUMAN STUDIES OF AD/HDMultiple lines of evidence suggest that genetic factors playmajor roles in the etiology of AD/HD; the heritability for thisdisorder was found 0.85—0.90.