SOX2 regulates multiple malignant processes of breast cancer development through the SOX2/miR-181a-5p, miR-30e-5p/TUSC3 axis

Kuancan Liu,Fuan Xie,Anding Gao,Rui Zhang,Long Zhang,Zhangwu Xiao,Qiong Hu,Weifeng Huang,Qiaojia Huang,Baoshun Lin,Jian Zhu,Haikun Wang,Jianwen Que,Xiaopeng Lan

SOX2 regulates multiple malignant processes of breast cancer development through the SOX2/miR-181a-5p, miR-30e-5p/TUSC3 axis

2017

Kuancan Liu
Fuan Xie
Anding Gao
Rui Zhang
Long Zhang
Zhangwu Xiao
Qiong Hu
Weifeng Huang
Qiaojia Huang
Baoshun Lin
Jian Zhu
Haikun Wang
Jianwen Que
Xiaopeng Lan

Background High levels of SOX2 protein are correlated with increased dissemination of breast cancer. However, the underlying molecular mechanisms are not fully understood.

Keywords:

Breast cancer
CA15-3
Cancer research
SOX2
Biology
RNA interference
Cell growth
Membrane protein
microRNA
Oncology
Signal transduction
Internal medicine
Cancer
Downregulation and upregulation
Gene knockdown

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