Mesenchymal Stem Cell Genetic Engineering and Regenerative Medicine

Characteristic properties of mesenchymal stem cells (MSCs) make them a suitable candidate in regenerative medicine. There are various associated limitations in MSCs in vivo applications like their short survival and limited expression of particular genes. Genetic engineering of MSCs may be employed to address such issues. Various genetic engineering methods have been incorporated although without any established standard technique. Genetically engineered MSCs are being studied in various kinds of ailments of different tissues with variably promising results. The current chapter focusses on the MSC genetic engineering in relation to the regenerative medicine.