Phenazopyridine hydrochloride crystal compound and pharmaceutical composition tablet thereof

2011 
The invention relates to a phenazopyridine hydrochloride crystal compound and a pharmaceutical composition tablet thereof. An X-ray powder diffraction of the phenazopyridine hydrochloride crystal compound obtained by a Cu-K alpha ray measure shows characteristic peaks at a 2 theta of 6.2 DEG, 9.9 DEG, 11.3 DEG, 14.8 DEG, 17.4 DEG, 19.9 DEG, 21.6 DEG, 27.4 DEG, and 29.6 DEG. The invention also relates to a pharmaceutical composition tablet containing the crystal. 1000 tablets comprise 80-120g of phenazopyridine hydrochloride crystal compound, 40-60g of starch, 20-40g of microcrystalline cellulose, 10-30g of low-substituted hydroxy propyl cellulose, 40-60ml of ethanol, 5-15g of sodium carboxymethyl starch and 2-4g of magnesium stearate. The phenazopyridine hydrochloride crystal compound of the invention has advantages of high water-solubility, and can increase medicament absorption speed in human body.
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