Multiplatform assessment of anaplastic lymphoma kinase (ALK) gene rearrangement in signet ring cell carcinoma of the gastrointestinal tract.

Olatunji B. Alese,Bassel F. El-Rayes,Gabriel Sica,Guojing Zhang,Michael R. Rossi,Volkan Adsay,Dianne Alexis,Francisco G. La Rosa,Marileila Varella-Garcia,Zhengjia Chen,John S. Kauh,Suresh S. Ramalingam,Fadlo R. Khuri,Taofeek K. Owonikoko

Multiplatform assessment of anaplastic lymphoma kinase (ALK) gene rearrangement in signet ring cell carcinoma of the gastrointestinal tract.

2017

Olatunji B. Alese
Bassel F. El-Rayes
Gabriel Sica
Guojing Zhang
Michael R. Rossi
Volkan Adsay
Dianne Alexis
Francisco G. La Rosa
Marileila Varella-Garcia
Zhengjia Chen
John S. Kauh
Suresh S. Ramalingam
Fadlo R. Khuri
Taofeek K. Owonikoko

e14612 Background: ALK-EML4 translocation is an established driver aberration in NSCLC, with reported predilection for cases with signet ring histology. We assessed the presence of ALK gene rearran...

Keywords:

Gastrointestinal tract
Pathology
Signet ring cell carcinoma
ALK Gene Rearrangement
Histology
Chromosomal translocation
Anaplastic lymphoma kinase
Medicine
signet ring

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