THIAZOLE COMPOUND AS PPARDelta; LIGAND AND PHARMACEUTICAL, COSMETIC AND HEALTH FOOD COMPRISED THEREOF

2008 
A thiazole compound as a PPARdelta(peroxisome proliferator activated receptor delta) ligand is provided to be used for treating obesity, hyperlipidemia, arteriosclerosis, diabetes, dementia, Alzheimer's and Parkinson's disease and for strengthening muscles or improving memory. A thiazole compound is represented by a formula(1). A pharmaceutical composition for preventing and treating arteriosclerosis, hyperlipidemia, diabetes, obesity, dementia, Alzheimer's disease or Parkinson's disease or for increasing the level of high density lipoprotein(HDL) or for enhancing endurance comprises the thiazole compound or a pharmaceutically acceptable salt thereof as an effective ingredient. A health food adjuvant or health beverage comprises the thiazole compound or a pharmaceutically acceptable salt thereof as an effective ingredient. A food additive or an animal feed or functional cosmetic composition comprises the thiazole compound or a pharmaceutically acceptable salt thereof. A PPARdelta activator composition comprises the thiazole compound or a pharmaceutically acceptable salt thereof.
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