Transdermal Drug Delivery System -A Review

In recent years a wide variety of newer drug delive ry system like sustained/controlled release dosage forms are designed and evaluated in order to overcome the lim itation of conventional therapy. These products are able to maintain steady drug plasma level s for extended periods of time as a result the vari ation of the drug levels in the blood are prevented and minimized drug related side effects. Controlled release drug delivery system p rovides a predictive control over the release pattern, and su bsequent t issue or blood levels can be achieved. One of the systems which provide controlled release of drug is transdermal drug delivery systems. Depending on th e therapeutic target, transdermal drug delivery syste ms (TDDS) are designed to provide a continuous supp drug through the skin to allow for local or systemi c drug effects. Transdermal drug delivery system (T DDS) is a novel approach for delivering drugs across the skin . Most of the drugs are administered orally and are found not ected. This review article describes briefly about the modes of drug administration, advantages and disadvantages of TDDS, drug penetration pathways, types of Transdermal Delivery Systems and Conventional therapy, Controlled release, Therapeut ic target, Transdermal