STUDIES ON THE TRANSFUSION OF RED CELL SUSPENSION IN SURGERY

The medical value of red cell suspension could be evaluated by the kind of solution which was used as a suspension of red cells.The authors have investigated the proprieties of several solutions for suspending the red cells, especially the preservability of these cells in them.It has been found that Pereston N, a saline solution of low molecule P. V. P., was the best for this purpose and 6% Dextran was next. It was also possible to use the solution of aminoacid crystals. These red cell suspensions were used in 130 cases of chronic anemia with excellent results.So far, it has been practically contraindicated in patients with anemia with hypoproteinemia and for operation or hemorrhage. However, we have had 22 clinical cases receiving massive transfusions of red cell suspensions in several kind of major surgical operations with good results without causing edema or tendency of bleeding.Warnings have been given repeatedly against massive and frequent administration of high molecule colloid solution because there was the possibility of its deposit in tissues. Thday we believe Pereston N is the most suitable solution for massive and frequent transfusions of red cell suspension.