VALIDATION OF AN ASSESSMENT TOOL FOR CONTROL IN COPD: ANALYSIS OF CLINICAL VARIABLES.
2018
Introduction: Clinical control in COPD has recently been proposed. However the original criteria (OCC) are too restrictive. Objective: Define and validate a new tool to assess COPD control using "modified" criteria (MCC) and assess its value as a risk predictor. Methodology: Prospective observational study in a cohort of COPD patients. Control is defined as the presence of low clinical impact and clinical stability. The adjustment for disease-severity and the best cut-off point in each item was evaluated to define the MCC. Patients were followed during 12 months. Time to event (composite outcome of emergency visit, hospitalization or death) was evaluated using cox regression analysis. Results: A total of 265 patients were included, 224 (83.9%) men, with a mean age (± SD) of 68 ± 9 years and FEV1 of 58 ± 17%. Percentage of control according OCC was 27,5% and for MCC: 61,5% with adjustment by BODEx index and 59,6% with adjustment by FEV1(%). Time to event (figure 1) was significantly greater in patients controlled with MCC criteria (p Conclusions: With the use of MCC a higher rate of controlled COPD patients is identified, compared to OCC. These patients have a lower risk of future events. Figure 1. Time to event (emergency visit, hospitalization or death) using modified control criteria, with adjustment by FEV1% (MCC-F)
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