Synthesis of Stable Cholesteryl–Polyethylene Glycol–Peptide Conjugates with Non-Disperse Polyethylene Glycol Lengths

Edgar Cristóbal-Lecina,Daniel Pulido,Pau Martin-Malpartida,Maria J. Macias,Fernando Albericio,Miriam Royo

Synthesis of Stable Cholesteryl–Polyethylene Glycol–Peptide Conjugates with Non-Disperse Polyethylene Glycol Lengths

2020

Edgar Cristóbal-Lecina
Daniel Pulido
Pau Martin-Malpartida
Maria J. Macias
Fernando Albericio
Miriam Royo

A method for conjugating cholesterol to peptide ligands through non-disperse polyethylene glycol (ND-PEG) through a non-hydrolysable linkage is described. The iterative addition of tetraethylene gl...

Keywords:

Conjugate
Combinatorial chemistry
peptide ligand
Polyethylene glycol
Peptide
Chemistry
Polyethylene

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