Intratumor Pressure in Hepatocellular Carcinoma

Intratumor pressure and hepatic tissue pressure were measured intraoperatively in 50 patients with hepatocellular carcinoma. Changes in these pressure were monitored before and after individual occlusion of the proper hepatic artery and the portal vein. Our result indicated that intratumor pressure was regulated predominantly by hepatic arterial blood flow, and increased with tumor capsular formation. In contrast, hepatic tissue pressure was regulated predominantly by portal blood flow, and increased with portal vein pressure.