High-dose fentanyl does not adversely affect outcome from forebrain ischemia in the rat.

SummaryFentanyl citrate has properties, including agonism of the μ-opioid receptor and proconvulsant activity, that theoretically could pose adverse effects in ischemic brain. This study examined the effects of high-dose fentanyl on outcome in rats subjected to transient near-complete forebrain isch