Self-Management Among Pre-teen and Adolescent Diabetes Device Users.

2020 
OBJECTIVE Despite increased diabetes device use, few adolescents with type 1 diabetes (T1D) meet glycemic targets.We examine associations between utilization of insulin pumps and continuous glucose monitoring (CGM) and glycemic control. RESEARCH DESIGN AND METHODS This prospectivecohort study included 80 youths (10-18 years of age) with T1D. Multiple linear regression and linear mixed models (LMM) were used to estimate the effects of device self-management on HbA1c and daily time in range (70-180 mg/dL), respectively. RESULTS Every blood glucose (BG) input/day was associated with a 0.2% decrease in HbA1c (95% CI: -0.297, -0.013), each bolus/day was associated with a 0.2% decrease (-0.327, -0.057), and use of CGM was associated with a 0.5% decrease (-1.00, -0.075). Among CGM users (n = 45)every 10% increase in CGM use was associated with a 0.3% decrease in HbA1c (-0.390, -0.180). In LMM accounting for within subject and between subject variability, there was a negative association between BG input/day frequency (coefficient = -1.880, [-2.640, -1.117])and time in range. Residual random effects for CGM users were large showingtime in rangevaried between youth with a SD of 15.0% (3 hours and 36 minutes)(SE 2.029, [11.484, 19.530]). Time in range varied significantly from day-to-day with SD of 18.6% (4 hours and 40 minutes) (SE0.455, [17.690, 19.473]). CONCLUSIONS Device self-management behaviors among youth are significantly associated with both HbA1c and time in range.Our findings showing an association between reduced time in range and increased self-management behaviors is novel and deserves further investigation. This article is protected by copyright. All rights reserved.
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