Aggregation-induced Emission Fluorogen as Mammalian Cell Cytoplasmic Tracker with Long Retention Time and High Photo-stability

Fluorescent probes used for cell imaging are powerful tools in cell-based assays and research. In this study, we exhibited a water-soluble aggregation-induced emission fluorogen(AIEgen), BSPO-TPE, specifically stained cytoplasm in live cells and had an excellent photostability when compared to that of two widely used commercial fluorescent dyes. The long cytoplasm retention time of BSPO-TPE demonstrated its suitability as a live cell cytoplasm tracker.