BASELINE LABORATORY PARAMETER MODIFICATIONS ARE ASSOCIATED TO THE TRAINING RATE IN AMATEUR AND ELITE ATHLETES
2012
Objective: The goal was to observe the physiological adaptation to different levels of
physical activity vs sedentary subjects.
Design: We have evaluated the effect of different training rate on the modification of
the basal levels of hormonal, biochemical and haematological parameters in elite and
amateur men and women performing sport activity as well as on sedentary controls.
Partecipants: One hundred fifty-three subjects were enrolled in this study and divided
In three categories according to the level of weekly sport training and activity. Blood
Samples were obtained in rest condition for all the subjects.
Results: Data obtained show that some haematochemical and endocrine parameters
seems to be persistently modified and that exercise-induced changes depend on
gender and on the rate of training. In particular, modification of leukocyte population
percentages and reduction of glucose levels characterises both woman and men
athletes. An increase of creatinkinase (CK),due to skeletal muscle hypertrophy was
observed in highly trained men and women. In the group of amateur women, the CK
increase was accompanied by an increase in aspartate-amino-transferase (AST) and
alanine-amino-transferase (ALT). Gender and training rate specific endocrine adaptation (increase of thyroid-stimulating-hormone, estradiol and testosterone for men and decrease of cortisol and free-thyroxine for woman) profile was also identified.
Conclusion: All together these data strongly suggest that the screening of blood
parameters in athletes may be useful to establish a baseline to monitor the
physiological/metabolic challenge arising from training
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