MP05-12 RE-EXAMINING AN OLD TREND: THE ASSOCIATION OF HUMAN PAPILLOMAVIRUS AND BLADDER CANCER

INTRODUCTION AND OBJECTIVES:The Human Papilloma Virus (HPV) is a recognized carcinogenic factor. Previous studies have shown a possible association between HPV and bladder cancer, however HPV serology has not been reported. In this study, we assessed the correlation between bladder cancer and HPV positive serology.METHODS:Using NHANES, a large nationally-representative population-based survey, we gathered clinical and demographic data on all patients with a diagnosis of bladder cancer over from 2007-2010 and analyzed their HPV serology status. We assessed the effects of positive serologic results for HPV18, HPV16, HPV11, and HPV6 on the rates of bladder cancer diagnosis.RESULTS:Over the four-year period there was a weighted population of 155,650,000 Americans. The prevalence of HPV positive serology was as follows: HPV18 - 5.5%, HPV16 - 13.2%, HPV11 - 6.4%, HPV6 - 17.4%. There were 443,948 bladder cancer cases. Among cases there was a higher prevalence of male gender (80% vs 53%, p = 0.0056), Caucasian ra...