Iron-Catalyzed Synthesis of 2-[(2 E )-Hex-2-en-1-yl]cyclopentanone

An efficient synthesis of a widely used fragrance, 2-[(2E)-hex-2-en-1-yl]cyclopentan-1-one, has been developed on the basis of iron-catalyzed cross-coupling of 2-[(2E)-3-chloroprop-2-en-1-yl]cyclopentan-1- one with propylmagnesium bromide.