Abstract 14035: Renal Tubular Secretion and Cardiac Distribution of Dofetilide is Dependent on MATE1 Function

Muhammad Erfan Uddin,Yan Jin,Alice A. Gibson,Ingrid M. Bonilla,Cynthia A. Carnes,Shuiying Hu,Alex Sparreboom

Abstract 14035: Renal Tubular Secretion and Cardiac Distribution of Dofetilide is Dependent on MATE1 Function

2020

Muhammad Erfan Uddin
Yan Jin
Alice A. Gibson
Ingrid M. Bonilla
Cynthia A. Carnes
Shuiying Hu
Alex Sparreboom

Introduction: Dofetilide is a delayed rectifier potassium channel inhibitor used to treat patients with atrial fibrillation and flutter, and its use is associated with a risk of QT prolongation and...

Keywords:

Potassium channel
Cardiology
QT interval
Atrial fibrillation
Dofetilide
Medicine
Cardioprotection
Long QT syndrome
delayed rectifier
Internal medicine
Renal tubular secretion

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