Nanoparticles Advancing Cancer Immunotherapy

Abstract Cancer is a leading cause of death worldwide. There is significant interaction between cancer’s biology and the host immune system. When an individual suffers from cancer, the body’s immune system is reportedly functioning to facilitate the cancer progression rather than performing its usual function of fighting disease. Alongside surgery and radio chemotherapy, cancer immunotherapy is predicted to be an effective and lucrative approach to eliminating cancer. Presently, nanobased advanced immunotherapy has the potential to boost the efficacy of immune agents by overcoming several limitations, such as efficient drug delivery, associated with current immunotherapy. Moreover, multifunctional nanoparticle-mediated immune therapeutic agents can target cancer cells specifically, facilitate intracellular penetration, and enhance immunogenicity of antigens; they also have other advantages, such as enabling the tracking of therapy.