The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation

Mamta Tahiliani,Pinchao Mei,Rui Fang,Thiago Leonor,Michael S. Rutenberg,Fumiko Shimizu,Jing Li,Anjana Rao,Yujiang Shi

The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation

2007

Mamta Tahiliani
Pinchao Mei
Rui Fang
Thiago Leonor
Michael S. Rutenberg
Fumiko Shimizu
Jing Li
Anjana Rao
Yujiang Shi

The JmjC domain-containing protein SMCX (or JARID1C), implicated in X-linked mental retardation, has histone H3K4 tri-demethylase activity and functions as a transcriptional repressor.

Keywords:

Histone H2A
X chromosome
Histone
Histone H1
Demethylase
Histone code
Histone methyltransferase
Genetics
Gene
Biology
Histone deacetylase 2
Histone demethylase activity
Histone Demethylases
Chromatin immunoprecipitation

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

362

Citations