Внутрисемейные факторы риска развития бронхиальной астмы

To analyze spread and a pathogenic role of various risk factors (RF) influencing members of bronchial asthma (BA) patient’s family 19 sick persons and 23 their relatives were examined. Serum Ig A, G, M and E levels and the antioxidant activity (AA) of the blood were investigated. High levels of biological, environmental and psychosocial RF in the families examined have been shown. The BA patients unlike their descendants without BA had higher IgE level, more frequent breast-feeding, lower birthweight, lower income and bad microclimate in their families. Smoking, child viral infections, gastrointestinal diseases were observed in BA patients as often as in their descendants. Parents of the BA patients showed a prevalence of the environmental FR, a high IgE level and AA activation.