Study of TSH and prolactin in PCOS subjects: A case control study

Background: To assess serum TSH and Prolactin in women with PCOS in comparison with healthy women as controls and to find correlation between TSH & Prolactin in PCOS subjects. Materials and Methods: A comparative study including 30 women diagnosed as PCOS and 30 age and BMI matched healthy women as controls was conducted. The age group for the study was 18-35 years. Fasting blood samples were drawn to measure serum thyroid stimulating hormone(TSH) and prolactin. Results: Mean TSH and prolactin were found elevated in the PCOS cases compared to controls but they were not statistically significant. No significant correlation was found between TSH and prolactin. Conclusion: We could not find any significant correlation between serum TSH and serum prolactin. Further, studies with larger number of PCOS subjects will be beneficial. However monitoring of Prolactin & TSH in PCOS should be done. Keywords: T3, T4, TSH, Depression.