Eicosanoids : from biotechnology to therapeutic applications

Leukotriene A4 Hydrolase: A Key Enzyme in the Biosynthesis of Leukotriene B4 A. Wetterholm, et al. Lipoxygenases of Mice and Men C.D. Funk. The Physiological and Therapeutic Significance of Separate Pathways for Prostaglandin Synthesis D.L. De Witt. Assessment of Pharmacological Inhibition of PGHsynthases in Man P. Patrignani, et al. Metabolism of Eicosanoids in Mammalian Cells R.C. Murphy. New Approach in Immunometric Assays P. Pradelles, et al. Transcellular Biosynthesis of Archidonic Acid Metabolites: From in Vitro Investigations to in Vivo Reality J. Maclouf. Polymorphonuclearendothelial Cell Interactions and the Control of Coronary Vasculature A. Sala. Plateletactivating Factor Regulates Events at the Vascular Wall S.M. Prescott, et al. Studies of Isoprostane Biosynthesis in Man G. Ciabattoni, et al. N3 Fatty Acids: Antithromboxane Activity: Effects on Redox Status of Blood Cells M. Lagarde, et al. Receptors and Second Messengers for Cysleukotrienes S. Nicosia, et al. Prostanoid Receptors: Classification, Characterization and Therapeutic Relevance R.A. Coleman. Microvascular Actions and Interactions of Eicosanoids and Histamine in Inflammation P. Hedqvist, et al. 4 additional articles. Index.