A phase II study of lapatinib in patients with advanced biliary tree and hepatocellular cancer

Ramesh K. Ramanathan,Chandra P. Belani,Deepti A. Singh,Michael Tanaka,Heinz-Josef Lenz,Yun Yen,Hedy L. Kindler,Syma Iqbal,Jeff Longmate,Philip C. Mack,Georg Lurje,Regina Gandour-Edwards,Janet Dancey,David R. Gandara

A phase II study of lapatinib in patients with advanced biliary tree and hepatocellular cancer

2009

Ramesh K. Ramanathan
Chandra P. Belani
Deepti A. Singh
Michael Tanaka
Heinz-Josef Lenz
Yun Yen
Hedy L. Kindler
Syma Iqbal
Jeff Longmate
Philip C. Mack
Georg Lurje
Regina Gandour-Edwards
Janet Dancey
David R. Gandara

Purpose To evaluate the response to lapatinib, an inhibitor of epidermal growth factor receptors 1 and 2, in patients with advanced bilary tree cancer (BTC) and hepatocellular cancer (HCC).

Keywords:

Cancer
Epidermal growth factor
Epidermal growth factor receptor
Pharmacology
Progression-free survival
Cancer research
Tyrosine-kinase inhibitor
Lapatinib
Internal medicine
Endocrinology
Medicine
hepatocellular cancer
Oncology
Pathology
Phases of clinical research
Biliary tract
Receptor

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