G28 Ebola virus disease in children in Sierra Leone: A retrospective cohort study

Background The Ebola virus disease (EVD) outbreak in West Africa has claimed over 11000 lives with >27000 cases. Infected children Method A retrospective observational cohort was designed including all children Results 309 children aged 2 days to 12 years were admitted to EHUs and tested positive for EVD. Outcomes were available for 282 (91%). Mortality was 57% with 55% occurring at EHUs and 45% at ETCs. Lower age was a strong predictor of mortality (multivariable OR 1.74, 95% CI 1.04–2.93 comparing children aged 0- Conclusion This is the most comprehensive paediatric cohort of EVD to date, and the only cohort to incorporate data from both EHUs and ETCs. The importance of data sharing between sites cannot be overstated in order to identify potentially modifiable risk factors in both adults and children and guide future operational responses.