Radionuclide research on liver and kidney function in thyroid cancer after radioiodine therapy

A study was made of liver and renal function using radionuclide methods in 51 thyroid cancer patients on radio-iodine therapy. Multimodality examination of the patients revealed no clinical manifestations of hepatocellular and renal failure even in significant therapeutic activities up to 40 GBq and more. Hepatography and renography showed a decrease in absorptive and secretory hepatocytic function, an increase in the period of hippuran half-life and a decrease in total renal function. The revealed changes were of moderate nature, stable and related both to hypothyrosis and a radiation factor.