Correlation of semen parameters with inflammatory factors in the seminal plasma of obese males

Objective To investigate the influence of inflammatory factors on semen parameters in the seminal plasma of obese men. Methods Based on the body mass index (BMI), 171 males were divided into a normal group (BMI Results Sperm concentration was significantly decreased in the obesity group in comparison with the normal and overweight groups (［40.19 ± 24.05］ vs ［66.54 ± 34.81］ and ［57.73 ± 24.61］ ×10⁶/ml, P 0.05). Conclusions The levels of TNF-α and IL-6 are increased and that of VEGF decreased in the seminal plasma of obese males, which may affect the semen quality.