Combinatorial Chemistry: Part of the Evolution in Drug Discovery

Combinatorial chemistry, automated synthesis, high-throughput screening, the explosion of molecular targets from genomic research and advances in informatics have come together in an interdependent evolution to provide an enormous opportunity not only for the life sciences but also for the materials sciences as well. Drug discovery has been the initial focus of this revolution because high-speed chemistry has rapidly evolved to meet the compound demands of high throughput, low volume screening which had been put in place to support the mechanistic based targets from molecular biology.