Pharmacokinetics and Bioavailability of Tianeptine in the Elderly
1990
A balanced 2-way crossover study involving 12 elderly volunteers was used to determine the pharmacokinetic parameters of the antidepressant tianeptine following a single dose administered by oral and intravenous routes. Pharmacokinetic parameters of metabolite MC5, the C5 side-chain β-oxidation product of tianeptine, were simultaneously determined.
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