Acute myeloid leukemia with t(8;21)(q22;q22.1); runx1-runx1t1 with tuberculosis - A case report

Background: In patients suffering from malignancies incidence of tuberculosis is highest in cases of hematological malignancies in comparison to solid organ malignancies. 1 Despite the fact tuberculosis remains under-diagnosed condition in hematological malignancies like acute leukemia and it may be a cause of febrile neutropenia in these cases. Rescheduling and/or alterations in therapies are required in these cases. 2 Case History: A 16year old male diagnosed as case of AML with t(8;21)(q22;q22.1);RUNX1-RUNX1T1 was on therapy after 6 weeks interval from initiation of therapy he presented with fever, weakness, lymphadenopathy and cough with expectoration since 15 days. Keywords: Acute leukemia, Tuberculosis, AML with t(8 21)(q22;q22)RUNX1-RUNX1T1, Acute myeloid leukemia, Therapy.