Pathogenic distribution and resistance research of systemic inflammatory response syndrome patients of bacterial infection

Objective To investigate the distribution and resistance in patients with systemic inflammatory response syndrome (SIRS) induced by bacterial infection in the hospital respiratory ward.Methods A total of 632 SIRS patients were retrospectively analyzed from October 2006 to October 2007.Results 376 cases of SIRS (59.49%) were induced by infection,while 256 cases of SIRS (40.51%) were induced by non-infectional factors. The etiology of SIRS was identified in 76 patients (20.21%). Gram-positive coccus and gram-negative bacilli accounted for 68.42% (52/76) and 31.58% (24/76) respectively.Three main pathogenic bacteria were Staphylococcus aureus [23.68% (18/76)], Pseudomonas aeruginosa [19.73%(15/76)] and Acinetobacter baumanii [15.78% (12/76)]. Conclusions Main pathogenic bacteria of SIRS patients are Staphylococcus aureus and Pseudomonas aeruginosa. Key words: Systemic inflammatory response syndrome; Infection; Bacterium; Drug resistance