Androgen receptor and hepatocellular carcinoma

Androgen receptors appear to play a significant role in the hepatocarcinogenesis.Androgen receptors are found to be expressed in liver tumor,and the overexpression of androgen receptor is associated with poor prognosis.Recent researches have indicated that androgen receptors regulate various cellular events in liver carcinogenesis through various ways,and androgen receptor could be a potential cancer therapeutic target in hepatocellular carcinoma. Key words: Carcinoma, hepatocellular; Receptors, androgen; Gene expression regulation, neoplastic