Expansive pellet for effectively masking taste and preparation method thereof

The invention provides an expansive pellet for effectively masking taste. The expansive pellet is composed of medicine serving as an active ingredient and pharmaceutic adjuvant. The pellet provided by the invention is composed of the following components in percentage by weight: 0.15-10% of medicine raw material, 15-85% of filler, 12-80% of expanding agent, 0.15-0.6% of plasticizer, 0.5-0.8% of lubricant and 0.8-1.5% of adhesive. The yield of the taste masking pellet prepared by the invention is high and can reach 75-90%; and the production process is simple. The particle diameter of the prepared pellet is 300-800 microns, the pellet is poured into warm water before being taken, and the pellet immediately expands and continuously increases. The expansion volume can reach 100-700% to generate a good visual effect. The pellet is taken after expanding, so that the taste is smooth, the pellet has certain elasticity to be beneficially swallowed and can effectively mask the bitter taste and unpleasant taste of the medicine so as to easily eliminate the rejection feeling of the elders, the patients having swallowing difficulty and especially children on the medicine with bitter taste and unpleasant taste, and the pellet is particularly suitable for medicine with bitter taste and unpleasant taste. The method disclosed by the invention is simple and is suitable for industrial production.