Relation of crp, ferritin and procalcitonin level in people infection with covid-19

Introduction: Since December 2019, the coronavirus disease 2019 (COVID‐19) caused by the severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) has rapidly developed into a global outbreak characterized by a human‐to‐human transmission. On March 11, 2020, WHO declared the COVID‐19 a pandemic. It has caused a total of 30 675 675 confirmed cases, including 954 417 deaths as of September 20, 2020. Patients with comorbidities such as diabetes, cardiovascular disease, underlying respiratory diseases, and cancer are at high risk of severe complications and even death. This is a global crisis that requires the joint efforts of all mankind to fight it. Method: This study was a descriptive study, conducted in the respiratory Department and molecular Research laboratory at Datta Meghe medical college (DMMC) Wanadongri, Nagpur and Shalinitai Meghe hospital and research center (SMHRC), Nagpur in collaboration with ABVRH, Sawangi (Meghe). Result: The Present study showed the relationship between the age factor and the prevalence of infection with the COVID virus-19, as the virus can infect all age groups, but the age group (20-79) years were the most affected age (26/68) 38.23%. Also, the study shows that infection with the virus Covid-19 has a significant effect on the level of the serum Ferritin (p-value < 0.001) and in both sexes (520.25ng/ml in the Men, 460 ng /ml In the Female compared to the Control group (232.30 ng/ml,77.217 ng/ml), respectively. significant increase in the level of C-Reactive Protein (p – value< 0.001 as the protein level reached (46 .60 IU/ML) in infected people compared to the control group (2.41 IU / ML). The current study coronavirus infection caused a significant increase level of PCT (P-value < 0.001) as the PCT level (16.2 ng/ml) in infected people compared to the control group 0.16 ng /ml. Conclusion: We conclude from the current study that the age and gender factor play an important role in the prevalence of Covid-19 infection and that Covid-19 infection causes an increase in both the effective protein level C, PCT the level of the ferritin of blood, so it can be relied upon in the early diagnosis of COVID-19 infection.