Theranostics Targeting Metastatic Breast Cancer

Abstract : This application is designed to impact three of the overarching challenges identified for this award type: (i) revolutionary treatment regimes replacing drugs that have life-threatening toxicities with safe and effective interventions; (ii) elimination of mortality associated with metastatic breast cancer; and, (iii) distinguishing aggressive breast cancer from indolent forms, to avoid over-diagnosis and treatment. Overall, this work addresses issues that relate to: (i) revolutionary treatment regimes replacing drugs that have life-threatening toxicities with safe and effective interventions; (ii) elimination of mortality associated with metastatic breast cancer; and, (iii) distinguishing aggressive breast cancer from indolent forms, to avoid over-diagnosis and treatment.