Enzymatic resolution of cis- and trans-4-hydroxycyclopent-2-enylmethanol derivatives and a novel preparation of carbocyclic 2′,3′-dideoxydidehydronucleosides and aristeromycin
1991
The (1R, 4S)-acetate 3 and the (1S, 4S)-alcohol 5 have been obtained optically pure by lipase catalysed esterification: compounds 3 and 5 have been converted into carbocyclic dideoxydidehydronucleosides and aristeromycin 9.
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