Life expectancy and early detection of neoplasia: One stop screening for multiple cancer types—11 year (2006-2017) experience of an integrated cancer prevention center (ICPC).

e13553Background: Cancer is the leading cause of mortality worldwide. Methods: Screening of healthy individuals (20-80 years) at the ICPC included 11 most common cancer types. Extensive clinical and epidemiological data was obtained. Peripheral blood DNA was genotyped for APC I1307K and E1317Q. Subjects were examined by specialists in internal medicine, surgery, plastic surgery, OBGYN, urology, oncology, oral surgery, gastroenterology, and others when indicated. Women (all ages) underwent vaginal US and pap smear and (40 yr) mammography and US/MRI when indicated. PSA and free PSA for Men ( > 40 yr). LDCT for heavy smokers. Colonoscopy to all subjects ( > 40 yr). Results: 7067 (49.4%) men and 7240 women mean age 46.69±11.5 years. 647 new lesions were detected among 602 (4.21%). Over half of them were malignant (366, 56.6%). Skin (105, 0.73%), breast (44, 0.31%), prostate (35, 0.24%), thyroid (31, 0.22%), CRC (24, 0.17%), ovarian (19, 0.13%), urinary (17, 0.12%), lung (15, 0.10%), hematology (15, 0.10%), ce...