Genotoxic evaluation of lambda-cyhalothrin in Mystus gulio

Genotoxic potential of pyrethroid pesticide lambda cyhalothrin (Karate) on Mystus gulio was studied using chromosomal aberration test in the gill cells. Fishes exposed in vivo to 6.4 ppb (10% 96hr LC 50 ) concentration of compound and sacrificed at four different sampling times 24, 48, 72, and 96 hr against the parallel-untreated tap water control. The different types of aberrations observed were chromatid breaks, centromeric fusion, acentric fragments, chromosomal gaps, sticky plates, aneuploidy and ring chromosomes. Chromosomal aberrations were found to be significantly increased in number than in control, and are statistically significant at (p<0.05) level.