TGF-beta Regulates Alternative Splicing of CD44 by Inducing Smad3 Binding to CD44 pre-mRNA

Ying Zhang,Veenu Tripathi,Katherine Sixt,Mary Heller

TGF-beta Regulates Alternative Splicing of CD44 by Inducing Smad3 Binding to CD44 pre-mRNA

2015

Ying Zhang
Veenu Tripathi
Katherine Sixt
Mary Heller

During late stage of breast cancer, TGF-beta signaling promotes tumor progression by stimulating EMT, cell invasion and disseminations to distant sites. Previous studies have showed that TGF-beta s...

Keywords:

Tumor progression
Internal medicine
Diabetes mellitus
Breast cancer
Precursor mRNA
Endocrinology
Cell
Biology
Alternative splicing
CD44
Cancer research
TGF beta signaling pathway
late stage

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