The effects of evidence - based nursing on prevention of the side - effect of chemotherapy assisted by amifostine

Objective To study if the evidence - based nursing could relieve the side - effect of chemotherapy assisted by amifosfine.Methods Evidence - based nursing and usual care were used to interfere the side - effects of chemotherapy assisted by amifostine in 66patients with cancer.The patients were divided into non - intervention group with accepted usual care ( 33 cases) and intervention group (33 cases) with evidence -based nursing.And side- effects of the chemotherapy of the two groups were compared.Results The incidence of hypotension,nausea,vomiting,dizziness,anergy,hypocalcemia in the intervention group were lower than those in non - intervention group (P =0.00) besides the fever index (t =1.0,P =0.32).Conclusions Evidence - based nursing and related prognostic treatments could decrease the side - effects of chemotherapy assisted by amifostine. Key words: Amifostine;  Side - effect;  Evidence - based nursing