Recurrently deregulated lncRNAs in hepatocellular carcinoma

Yang Yang,Lei Chen,Jin Gu,Hanshuo Zhang,Jiapei Yuan,Qiuyu Lian,Guishuai Lv,Siqi Wang,Yang Wu,Yucheng T. Yang,Dongfang Wang,Yang Liu,Jing Tang,Guijuan Luo,Yang Li,Long Hu,Xinbao Sun,Dong Wang,Mingzhou Guo,Qiaoran Xi,Jianzhong Xi,Hongyang Wang,Michael Q. Zhang,Zhi John Lu

Recurrently deregulated lncRNAs in hepatocellular carcinoma

2017

Long noncoding-RNAs have been linked to hepatocellular carcinoma (HCC) and some can be used as prognostic markers. Here the authors, by analysing RNA-seq in 60 clinical samples from 20 patients, provide a resource of functional lncRNAs and biomarkers associated with HCC tumorigenesis and metastasis.

Keywords:

Hepatocellular carcinoma
Carcinogenesis
Biology
Metastasis
Immunology
Biomarker (medicine)
Cancer research
DNA methylation
Liver cancer
Bioinformatics
Gene expression profiling
Copy-number variation
Genetics

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