A Meta-analysis of Effectiveness Evaluation between Shexiang Baoxin Pill and Isosorbide Mononitrate Tablet

Objective To compare the efficacy of Shexiang Baoxin Pill (SBP) with isosorbide mononitrate tablet (ISM) in the clinical treatment of angina pectoris of coronary heart disease and the ratio of electrocardiogram (ECG) improvement in patients. Methods Systematically searched EMBASE, MEDLINE, PubMed, CBM, VIP, Wanfang and CNKI databases from 2000 to 2016 to collect all relevant studies. According to the Cochrane Handbook for systematic reviews, quality assessment and data extraction were precise. All data were analyzed by using Review Manager 5.2. Results The results showed that SBP had a significant effect on the total effective rate (7 trials, n = 874, OR = 0.31, 95% CI: 0.21–0.46, P < 0.05) and on the ECG improving rate (4 trials, n = 437, OR = 0.39, 95% CI: 0.20–0.49, P < 0.05), which compared with ISM in the clinical treatment of angina pectoris of coronary heart disease. Conclusion SBP had a better effect than the ISM in the treatment of angina pectoris of coronary heart disease in terms of total effective rate and ECG improving rate.