Синтез и свойства тиопроизводных 5-нитропиримидина. Строение и особенности превращений борсодержащих тиопиримидинов

A series of 5-nitropyrtimidine (5-NP) thioderivatives were synthesized via the reactions of chlorine-substituted 5-NPs with various aromatic and boron-containing thiols. Reactions of 4,6-dithioderivatives of 5-NPs with nucleophiles were studied. Stable 2-σ-adducts were obtained using a boron-containing 4,6-dithioderivative of 5-NP. The interaction of an aromatic sulfide of 5-NP with 1-phenyl-3-methylpyrazolone led to the substitution at one of the arylthio groups. The NMR and mass spectra of the synthesized compounds were obtained; 2-oxy-σ-adduct was characterized by x-ray diffraction.