Validation of secondary dose calculation system with manufacturer-provided reference beam data using heterogeneous phantoms

The Mobius3D (M3D) system (Mobius Medical Systems) is a second-check dosimetry system. We investigated the dose calculation accuracy of this system using heterogeneous phantoms with reference beam data provided by the manufacturer using simple and patient plans. We compared the dose distributions between M3D and the treatment planning system, as well as the measurements in solid water phantoms, heterogeneous phantoms, and patient plans for Varian and Elekta accelerators. The M3D results agreed well with the measurements in the solid water phantoms for the simple plans. However, the accuracy of M3D appeared to depend on the type of accelerator, as indicated by the slight differences in the dose measurements. Furthermore, the M3D dose measurements differed by 5–10% in the lung and bone regions. Regarding the patient plans, we confirmed that M3D is reasonably accurate as a second-check system, despite the slight accelerator type-dependent dose difference.