Pharmacokinetics of inhaled colistin in critically ill patients with ventilator-associated tracheobronchitis

Although inhaled colistin is frequently used in ventilator-associated pneumonia (VAP), data regarding its pharmacokinetic properties are scarce [1-3]. The aim of this study was to describe colistin pharmacokinetics in critically ill patients after administration of a single dose of 1 million units of colistimethate sodium (CMS) via nebulization.