MP33-18 “THE ROLE OF RENAL TUBULAR CELL INJURY IN THE EARLY PERIOD OF RENAL CRYSTAL FORMATION” IDENTIFIED FROM THE CELL INJURY-INHIBITING EFFECT OF GREEN TEA

RESULTS: The examinations at every weekend showed that Ox of 24 hours urine did not change significantly in both Group A and B£P>0.05£ , Group C and D were significantly lower than those in group B (P 0.05£ £Group C and D were significantly increased compared with those in Group B(P<0.05), Group D increased more significantly than that Group C (P<0.05). There were no significant changes of the renal function and serum Ca2þ of rats in all groups. The CT post-processing workstation data analysis suggested that the average CT value of Group B were significantly higher than Group D, and both of the two groups were higher than Group A; The differences were more obvious in conditions of low-kilovolt (P<0.05). The calcium oxalate crystal of tubules in Group B wer more serious than in Group C and D, and Group C were more serious than Group D. There were no significent calcium oxalate crystal deposition and pathological changes in renal biopsy specimens of Group A. CONCLUSIONS: Oxalate-degrading enzymes can effectively reduce the formation of calcium oxalate kidney stones in intestinal hyperoxaluria rat.