Immunohistochemical study on the CD45 marker in human periodontal ligament stem cells.

Abstract Aim: The present study was undertaken to evaluate immunohistochemically the presence or absence of CD45 in human periodontal ligament cells. Methodology: In the present study, samples were obtained from the periodontal ligament of 10 extracted premolars of five healthy patients aged 15 to 28 years, after obtaining written informed consent from the patient. The teeth were extracted for orthodontic reasons. These were then processed and stained immunohistochemically for detection of cell surface marker namely CD 45. Results: The results clearly showed the absence of CD45 in the periodontal ligament stem cells in all the samples. Conclusion: It may be inferred from the above study the absence of CD45 markers is noted in the periodontal ligament stem cells and is one of their characteristic features.