A method for the prevention or treatment of intractable inflammatory bowel disease

The present invention aims to provide a prophylactic and therapeutic methods of steroid resistant or steroid dependent inflammatory bowel disease. A method of preventing or treating the inflammatory bowel disease in a patient in need of prevention or treatment of steroid resistant or steroid dependent inflammatory bowel disease, an effective amount of adrenomedullin, steroid resistant a modification thereof or those with steroid-dependent inflammation suppressing activity, or the prevention or treatment comprising administering a salt thereof those with steroid resistant or steroid dependent inflammation inhibiting activity in said patient it is possible to solve the problems by a method.