Clinical Characteristics and Outcomes of 821 Older Patients With SARS-Cov-2 Infection Admitted to Acute Care Geriatric Wards: A Multicenter Retrospective Cohort Study

Background There is limited information describing the characteristics and outcomes of hospitalized older patients with confirmed coronavirus disease 2019 (COVID-19) Method We conducted a multicentric retrospective cohort study in 13 acute COVID-19 geriatric wards, from March 13 to April 15, 2020, in Paris area All consecutive patients aged 70 years and older, with confirmed COVID-19, were enrolled Results Of the 821 patients included in the study, the mean (SD) age was 86 (7) years;58% were female;85% had ≥2 comorbidities;29% lived in an institution;and the median [interquartile range] Activities of Daily Living scale (ADL) score was 4 [2–6] The most common symptoms at COVID-19 onset were asthenia (63%), fever (55%), dyspnea (45%), dry cough (45%), and delirium (25%) The in-hospital mortality was 31% (95% confidence interval [CI] 27–33) On multivariate analysis, at COVID-19 onset, the probability of in-hospital mortality was increased with male gender (odds ratio [OR] 1 85;95% CI 1 30–2 63), ADL score <4 (OR 1 84;95% CI 1 25–2 70), asthenia (OR 1 59;95% CI 1 08–2 32), quick Sequential Organ Failure Assessment score ≥2 (OR 2 63;95% CI 1 64–4 22), and specific COVID-19 anomalies on chest computerized tomography (OR 2 60;95% CI 1 07–6 46) Conclusions This study provides new information about older patients with COVID-19 who are hospitalized A quick bedside evaluation at admission of sex, functional status, systolic arterial pressure, consciousness, respiratory rate, and asthenia can identify older patients at risk of unfavorable outcomes