Microwave irradiation in solvent-free conditions: Preparation of 2-substituted 4(3 H )-quinazolinones by heterocyclisation of 2- aminobenzamide with carboxylic acids
2004
A simple and fast preparation of 2-substituted-4(3H)-quinazolinones in high yields has been developed by microwave induced heterocyclisation of 2-aminobenzamide with carboxylic acids in solvent-free conditions. In comparison, the reactions are 40-80 times faster under microwave irradiation and the yields are much higher than conventional heating.
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